P-(Trifluoromethyl)Chlorobenzene
Linshang Chemical
HS Code |
409430 |
Chemical Formula | C7H4ClF3 |
Molecular Weight | 180.55 |
Appearance | Colorless liquid |
Boiling Point | 154 - 156 °C |
Density | 1.32 g/cm³ |
Solubility In Water | Insoluble |
Flash Point | 46 °C |
Refractive Index | 1.435 |
As an accredited P-(Trifluoromethyl)Chlorobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
Packing | 1 - kg bottle of P-(trifluoromethyl)chlorobenzene, securely packaged for safe transit. |
Storage | P-(trifluoromethyl)chlorobenzene should be stored in a cool, well - ventilated area away from heat, sparks, and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant materials. Avoid storing it near oxidizing agents. This helps prevent evaporation, potential ignition, and reactions that could lead to hazardous situations. |
Shipping | P-(trifluoromethyl)chlorobenzene is shipped in specialized, tightly - sealed containers. Compliance with strict chemical shipping regulations is crucial to prevent leakage and ensure safe transport due to its chemical nature. |
Competitive P-(Trifluoromethyl)Chlorobenzene prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com


As a leading P-(Trifluoromethyl)Chlorobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
Bearing the brunt, this compound has extraordinary effects in the synthesis of medicine. It can be used as a key intermediate to help create many specific drugs. Taking some anti-cancer drugs as an example, the special chemical structure of P - (trifluoromethyl) chlorobenzene can make the drug act more accurately on cancer cell targets, improve drug efficacy, and reduce damage to normal cells, so this compound plays a crucial role in the development of anti-cancer drugs.
Furthermore, it also plays a key role in the manufacture of pesticides. Due to its unique chemical properties, it can be used to prepare high-efficiency, low-toxicity and environmentally friendly pesticides. Such pesticides can effectively kill pests and protect crops from damage, while having little negative impact on the ecological environment, contributing to the sustainable development of agriculture.
In addition, in the field of materials science, P - (trifluoromethyl) chlorobenzene also has its uses. It can be used to synthesize polymer materials with excellent performance, such as materials with excellent heat resistance, corrosion resistance and electrical properties. These materials are widely used in high-end fields such as electronics, aerospace, etc., providing strong support for the development of related industries.
In conclusion, P- (trifluoromethyl) chlorobenzene has shown important uses in many fields such as medicine, pesticides, and materials science, and is of great significance in promoting the progress of various industries.
This compound is mostly colorless to slightly yellow liquid at room temperature. It looks clear and translucent, just like pure water, but it contains unique chemical properties. Its odor is specific or slightly irritating, but this is also one of its signs.
As for its melting point, the melting point is quite low, and it is difficult to solidify at room temperature, just like the agile water, which always maintains a flowing state. The boiling point varies depending on the compound's own structure and external pressure, and roughly evaporates and converts into a gaseous state within a certain temperature range.
In terms of density, compared to water, there is a slight difference. It can float or sink in a liquid, depending on the characteristics of this density. Solubility is also one of the key physical properties. In organic solvents such as ethanol and ether, it can exhibit good solubility, just like fish entering water and freely blending; however, in water, the solubility is poor, and the two are difficult to mix.
In addition, the compound has a certain volatility, which is slowly emitted in the air, like an invisible breath, quietly diffusing. And because its molecular structure contains fluorine, chlorine and other elements, it has a certain stability and is not prone to violent chemical changes in general environments. These physical properties lay the foundation for their application in many fields such as organic synthesis and materials science, and are indeed indispensable substances in the chemical world.
The physical properties of this compound are unique. Under normal circumstances, it is mostly in the form of a colorless and transparent liquid, and the appearance is clear and clear. Smell it, it has a special smell. Although it is not rich and fragrant, it is also unique. Its boiling point value is within a specific range. This property is important in chemical operations such as distillation and separation.
As for the chemical properties, it is also very interesting. The electron cloud structure of the benzene ring is affected by trifluoromethyl and chlorine atoms, and has undergone significant changes. Trifluoromethyl, which has a strong electron-absorbing effect, is like a "strong predator" that pulls the benzene ring electron cloud in its own direction. Chlorine atoms, although they also have the ability to absorb electrons, are slightly inferior in comparison.
This change in the distribution of electron clouds decreases the density of the benzene ring electron cloud, just like the reallocation of resources. As a result, the activity of electrophilic substitution reactions decreases sharply. Taking the halogenation reaction as an example, compared with ordinary benzene, more severe reaction conditions, such as higher temperatures and more efficient catalysts, are required to facilitate the reaction.
However, this compound exhibits a unique affinity for nucleophilic substitution reactions. Due to the presence of trifluoromethyl and chlorine atoms in its structure, the benzene ring carbon atoms are partially positively charged, just like opening their arms and waiting for the "embrace" of the nucleophilic reagent. Once the nucleophilic reagent arrives, it is very easy to undergo nucleophilic substitution reactions, forming brand new compounds.
In the field of organic synthesis, P - (trifluoromethyl) chlorobenzene can be said to be a shining "star". As a key intermediate, it participates in the construction of many complex organic compounds and contributes indelibly to the development of organic synthesis chemistry.
First, p-chlorotoluene is used as the starting material, and trifluoromethyl is introduced through a special chemical reaction. In this process, specific reagents and precise reaction conditions are often required. The reagents used or special compounds containing fluoride need to be precisely controlled in the reaction environment. Temperature and pressure are controlled to ensure a smooth reaction and obtain the desired product. This reaction step is complicated and requires fine operation to prevent the growth of side reactions and impure products.
Second, p-chlorobenzoic acid is also used as the starting material. First, p-chlorobenzoic acid is converted into a specific intermediate product, and then trifluoromethyl groups are introduced through an ingenious reaction mechanism. This approach requires a good understanding of the reaction mechanism of each step, each step is related to the quality and yield of the final product.
There are also those who use other related compounds as starting materials and prepare through multi-step reactions. If an aromatic hydrocarbon with a similar structure is selected, its specific position is functionalized first, and then trifluoromethyl is introduced. This process requires careful selection of reaction sequence and conditions according to the characteristics of each compound to achieve efficient preparation.
The methods for preparing p- (trifluoromethyl) chlorobenzene, although each has a different path, all require a deep understanding of the chemical principle and rigorous operation in order to obtain products with high purity and good yield.
When hiding, the first environment. When choosing a cool, dry and well-ventilated place, avoid open flames and hot topics. Because of its heat or open flames, it is dangerous to live and cause unexpected disasters. The temperature and humidity of the warehouse should be carefully controlled. The temperature should not exceed 30 degrees Celsius, and the humidity should also be kept in a reasonable area to prevent it from changing due to humidity and heat.
Furthermore, this substance should be separated from oxidizing agents and alkalis, and must not be mixed. Due to its chemical properties, if it is mixed with them, or it may cause severe reactions, it will endanger the safety of storage.
When transporting, do not take it lightly. The carrier must have the corresponding qualifications, and the equipment used must be sturdy and tight to prevent leakage. Loading and unloading vehicles should be carried out with care to prevent them from being shaken, hit, and damaged packaging.
During the journey, drivers and escorts should strictly abide by the rules and always check the contents. In case of leakage, etc., take effective measures immediately. Evacuate people around first, set up warning signs, and prohibit unrelated people from approaching. Then according to the leakage, choose the appropriate method to deal with it, or cover it with sand, etc., or lead it to a safe place to neutralize.
In short, when storing and transporting - (trifluoromethyl) chlorobenzene, every step is related to safety, and it must be done in accordance with regulations, and there must be no slack at all, so as to ensure that everything goes smoothly and is harmless.

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