Linshang Chemical
PRODUCTS
R(-)-Alpha-(Chloromethyl)Benzenemethanol
Linshang Chemical
|
HS Code |
194511 |
| Chemical Formula | C8H9ClO |
| Molar Mass | 156.609 g/mol |
| Appearance | Colorless to light yellow liquid |
| Boiling Point | Approx. 225 - 230 °C |
| Density | Approx. 1.17 g/cm³ |
| Solubility In Water | Insoluble |
| Solubility In Organic Solvents | Soluble in common organic solvents like ethanol, ether |
| Flash Point | Approx. 99 °C |
| Chirality | Chiral compound with R(-) configuration |
| Functional Groups | Alcohol, Chloromethyl, Aromatic benzene ring |
As an accredited R(-)-Alpha-(Chloromethyl)Benzenemethanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of R(-)-α-(chloromethyl)benzenemethanol in a sealed, chemical - resistant bottle. |
| Storage | **Storage of (R)-(-)-α-(chloromethyl)benzenemethanol** Store (R)-(-)-α-(chloromethyl)benzenemethanol in a cool, dry, well - ventilated area away from sources of heat, ignition, and oxidizing agents. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to decomposition or reaction. Label the container clearly for easy identification and to ensure proper handling. |
| Shipping | "R(-)-α-(chloromethyl)benzenemethanol" is a chemical. Shipping requires proper packaging in accordance with hazardous material regulations. It should be labeled clearly, and shipped via carriers approved for chemical transport to ensure safety during transit. |
Competitive R(-)-Alpha-(Chloromethyl)Benzenemethanol prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
We will respond to you as soon as possible.
Tel: +8615365006308
Email: info@alchemist-chem.com
Where to Buy R(-)-Alpha-(Chloromethyl)Benzenemethanol in China?
As a trusted R(-)-Alpha-(Chloromethyl)Benzenemethanol manufacturer, we deliver:
Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements.
Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery.
Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
As a leading R(-)-Alpha-(Chloromethyl)Benzenemethanol supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of R (-) -alpha- (chloromethyl) benzenemethanol?
R （ - ） -α - （ chloromethyl) benzyl alcohol is also an organic compound. Its chemical structure is based on a benzene ring, the α position of the benzene ring is connected to a hydroxymethyl group, and a hydrogen atom on the methylene of the hydroxymethyl group is replaced by a chlorine atom. This compound is chiral and has an R configuration.
In its structure, the benzene ring is aromatic and consists of six carbon atoms connected by a conjugated π bond to form a six-membered ring structure, which endows the compound with certain stability and special chemical activity. The α position of α - (chloromethyl) benzyl alcohol is chiral due to the connection of different groups, and it presents a specific three-dimensional configuration in space. The R configuration is determined according to the Cahn-Ingold-Prelog rule. The connection of hydroxymethyl and chloromethyl to the benzene ring makes this compound have some chemical properties of alcohols and halogenated hydrocarbons. Alcohol hydroxyl groups can participate in reactions such as esterification and oxidation, while chlorine atoms of chloromethyl groups can undergo reactions such as nucleophilic substitution.
This structural feature determines that it has important uses in organic synthesis, medicinal chemistry and other fields. Due to its chirality, it can be used for asymmetric synthesis to prepare target products with specific three-dimensional configurations; in medicinal chemistry, chiral structures are often closely related to drug activity, or can be used as lead compounds to develop new drugs with high activity and low toxicity through structural modification and optimization.
In its structure, the benzene ring is aromatic and consists of six carbon atoms connected by a conjugated π bond to form a six-membered ring structure, which endows the compound with certain stability and special chemical activity. The α position of α - (chloromethyl) benzyl alcohol is chiral due to the connection of different groups, and it presents a specific three-dimensional configuration in space. The R configuration is determined according to the Cahn-Ingold-Prelog rule. The connection of hydroxymethyl and chloromethyl to the benzene ring makes this compound have some chemical properties of alcohols and halogenated hydrocarbons. Alcohol hydroxyl groups can participate in reactions such as esterification and oxidation, while chlorine atoms of chloromethyl groups can undergo reactions such as nucleophilic substitution.
This structural feature determines that it has important uses in organic synthesis, medicinal chemistry and other fields. Due to its chirality, it can be used for asymmetric synthesis to prepare target products with specific three-dimensional configurations; in medicinal chemistry, chiral structures are often closely related to drug activity, or can be used as lead compounds to develop new drugs with high activity and low toxicity through structural modification and optimization.
What are the main uses of R (-) -alpha- (chloromethyl) benzenemethanol?
R (-)-α-( chloromethyl) benzyl alcohol has a wide range of uses. In the field of medicinal chemistry, it is often an important synthesis intermediate. Through subtle chemical reactions, it can be ingeniously transformed to create various drugs with unique effects. For example, in the preparation of some compounds with specific therapeutic targets, R (-)-α-( chloromethyl) benzyl alcohol plays a key role. Through a series of reaction steps, it can precisely construct the specific structure of drug active molecules, helping drugs to exert the effect of treating diseases.
In the field of materials science, it also has its uses. Or it can participate in the synthesis of some functional materials, giving materials different properties. For example, by polymerizing with specific monomers, the material has unique physical and chemical properties, such as improving the solubility and stability of the material, and even affecting its optical and electrical properties, providing an important basis for the research and development of new materials.
Furthermore, in the field of organic synthesis, as an organic compound with a special structure, it provides a key starting material for the synthesis of many complex organic molecules. With its unique functional groups and chiral structures, chemists can carry out rich and diverse reaction path design to achieve stereoselective synthesis of the target product, so as to obtain organic compounds with specific configurations and functions to meet the needs of different fields for special organic molecules.
In the field of materials science, it also has its uses. Or it can participate in the synthesis of some functional materials, giving materials different properties. For example, by polymerizing with specific monomers, the material has unique physical and chemical properties, such as improving the solubility and stability of the material, and even affecting its optical and electrical properties, providing an important basis for the research and development of new materials.
Furthermore, in the field of organic synthesis, as an organic compound with a special structure, it provides a key starting material for the synthesis of many complex organic molecules. With its unique functional groups and chiral structures, chemists can carry out rich and diverse reaction path design to achieve stereoselective synthesis of the target product, so as to obtain organic compounds with specific configurations and functions to meet the needs of different fields for special organic molecules.
What are the physical properties of R (-) -alpha- (chloromethyl) benzenemethanol?
R (-)-α-( chloromethyl) benzyl alcohol, which is a kind of organic compound. Its physical properties are quite critical, let me elaborate.
Looking at its appearance, it is often colorless to light yellow liquid, like a light stream, pure without losing color. Its smell, with a special aroma, is like the hidden fragrance of mountains and forests. Although it is not strong, it is unique.
When it comes to the boiling point, it is about a specific temperature range, just like everything has its predetermined destination. This temperature makes it transform from liquid to gas, opening a different physical form change. The melting point also has its fixed value. At this temperature, it is like a calm rock, showing people in a solid state.
As for the density, compared to water, it has a specific specific gravity, or lighter than water, it seems to float lightly on water; or heavier than water, it quietly sinks to the bottom of the water. In terms of solubility, it shows good solubility in common organic solvents such as ethanol, ether, etc., just like fish entering water and blending freely; however, its solubility in water is relatively limited, just like the intolerance of oil and water, and the boundaries are clear.
Its refractive index also has a unique value. When light passes through it, it will be refracted at a specific angle, as if the light also follows the trajectory it has set. The many physical properties of
R (-)-α-( chloromethyl) benzyl alcohol together constitute its unique "identity mark", which provides many clues and basis for researchers to explore in the field of organic chemistry.
Looking at its appearance, it is often colorless to light yellow liquid, like a light stream, pure without losing color. Its smell, with a special aroma, is like the hidden fragrance of mountains and forests. Although it is not strong, it is unique.
When it comes to the boiling point, it is about a specific temperature range, just like everything has its predetermined destination. This temperature makes it transform from liquid to gas, opening a different physical form change. The melting point also has its fixed value. At this temperature, it is like a calm rock, showing people in a solid state.
As for the density, compared to water, it has a specific specific gravity, or lighter than water, it seems to float lightly on water; or heavier than water, it quietly sinks to the bottom of the water. In terms of solubility, it shows good solubility in common organic solvents such as ethanol, ether, etc., just like fish entering water and blending freely; however, its solubility in water is relatively limited, just like the intolerance of oil and water, and the boundaries are clear.
Its refractive index also has a unique value. When light passes through it, it will be refracted at a specific angle, as if the light also follows the trajectory it has set. The many physical properties of
R (-)-α-( chloromethyl) benzyl alcohol together constitute its unique "identity mark", which provides many clues and basis for researchers to explore in the field of organic chemistry.
What are the synthesis methods of R (-) -alpha- (chloromethyl) benzenemethanol?
There are many ways to synthesize R (-)-α-( chloromethyl) benzyl alcohol. In terms of ancient methods, one of them can be started from the corresponding aldehyde. If benzaldehyde is used as the starting material, it can be obtained by reacting with chloromethylation reagents, such as polyformaldehyde and hydrogen chloride, under specific conditions. This reaction requires attention to the precise control of the reaction temperature and the amount of reagents. If the temperature is too high or the reagent is excessive, it is easy to cause side reactions to breed. Then, the obtained α - (chloromethyl) benzaldehyde is reduced in an alcohol solvent with a suitable reducing agent, such as sodium borohydride, to obtain R (-)-α-( chloromethyl) benzyl alcohol. During operation, the addition speed and reaction time of the reducing agent need to be properly controlled to obtain higher yield and purity.
Second, it can be started from styrene. Shilling styrene reacts with hypochlorous acid or related chlorine oxidation reagents to generate β-chloroethanolbenzene derivatives. In this step, the pH of the reaction medium and the reaction time have a great influence on the selectivity of the product. Then, through the rearrangement reaction, the β-chloroethanolbenzene derivative is converted into alpha - (chloromethyl) benzyl alcohol. The conditions of the rearrangement reaction, such as the choice and amount of catalyst, the reaction temperature, etc., need to be finely adjusted to enable the reaction to proceed smoothly and tend to generate R (-)-α-( chloromethyl) benzyl alcohol of the target configuration.
Furthermore, the asymmetric synthesis method involving chiral catalysts is also a good strategy. Specific chiral ligands are selected to complex with metal catalysts to catalyze the reaction of corresponding precursor compounds. For example, the reaction of styrene derivatives with chloromethylation reagents using chiral ligands-containing metal catalysts can directly construct R (-)-α-( chloromethyl) benzyl alcohol with specific configurations. This method requires very high design and preparation of chiral catalysts, and requires in-depth consideration of the structure of chiral ligands, the types of metal ions and their interactions to achieve efficient and highly selective synthesis.
Second, it can be started from styrene. Shilling styrene reacts with hypochlorous acid or related chlorine oxidation reagents to generate β-chloroethanolbenzene derivatives. In this step, the pH of the reaction medium and the reaction time have a great influence on the selectivity of the product. Then, through the rearrangement reaction, the β-chloroethanolbenzene derivative is converted into alpha - (chloromethyl) benzyl alcohol. The conditions of the rearrangement reaction, such as the choice and amount of catalyst, the reaction temperature, etc., need to be finely adjusted to enable the reaction to proceed smoothly and tend to generate R (-)-α-( chloromethyl) benzyl alcohol of the target configuration.
Furthermore, the asymmetric synthesis method involving chiral catalysts is also a good strategy. Specific chiral ligands are selected to complex with metal catalysts to catalyze the reaction of corresponding precursor compounds. For example, the reaction of styrene derivatives with chloromethylation reagents using chiral ligands-containing metal catalysts can directly construct R (-)-α-( chloromethyl) benzyl alcohol with specific configurations. This method requires very high design and preparation of chiral catalysts, and requires in-depth consideration of the structure of chiral ligands, the types of metal ions and their interactions to achieve efficient and highly selective synthesis.
What is the market outlook for R (-) -alpha- (chloromethyl) benzenemethanol?
R (-)-α-( chloromethyl) benzyl alcohol, this product has considerable market prospects. It has a wide range of uses in the field of organic synthesis and is often used as a key intermediate in the preparation of medicine, pesticides and fine chemicals.
Looking at the pharmaceutical industry, the synthesis of many drugs depends on its participation. For example, a certain type of compound with specific biological activities, in its synthesis path, R (-)-α-( chloromethyl) benzyl alcohol is a key starting material. After a series of exquisite reactions, it eventually becomes a drug with outstanding efficacy. In the field of pesticides, it can be used to synthesize pesticide ingredients with high insecticidal and bactericidal properties to escort agricultural harvests.
In the field of fine chemicals, it also shows its talents. It can prepare fine chemicals such as fragrances and additives to add unique quality to people's daily use.
Furthermore, with the advancement of science and technology and the advancement of chemical technology, the research on its synthesis method continues to deepen, the production cost may gradually decrease, and the quality can also be steadily improved, which will definitely promote its market demand to rise. Coupled with the constant global demand for medicines, pesticides and fine chemical products, and the trend of growth, R (-)-α-( chloromethyl) benzyl alcohol is expected to expand into a wider world in the future market, with a bright future.
Looking at the pharmaceutical industry, the synthesis of many drugs depends on its participation. For example, a certain type of compound with specific biological activities, in its synthesis path, R (-)-α-( chloromethyl) benzyl alcohol is a key starting material. After a series of exquisite reactions, it eventually becomes a drug with outstanding efficacy. In the field of pesticides, it can be used to synthesize pesticide ingredients with high insecticidal and bactericidal properties to escort agricultural harvests.
In the field of fine chemicals, it also shows its talents. It can prepare fine chemicals such as fragrances and additives to add unique quality to people's daily use.
Furthermore, with the advancement of science and technology and the advancement of chemical technology, the research on its synthesis method continues to deepen, the production cost may gradually decrease, and the quality can also be steadily improved, which will definitely promote its market demand to rise. Coupled with the constant global demand for medicines, pesticides and fine chemical products, and the trend of growth, R (-)-α-( chloromethyl) benzyl alcohol is expected to expand into a wider world in the future market, with a bright future.
Scan to WhatsApp
