Linshang Chemical
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(S)-2,4-Dichloro-A-(Chloromethyl)-Benzenemethanol
Linshang Chemical
|
HS Code |
957155 |
| Chemical Formula | C8H7Cl3O |
| Molecular Weight | 225.5 g/mol |
| Appearance | Solid (likely white or off - white) |
| Physical State At Room Temperature | Solid |
| Solubility In Water | Low solubility (organic nature) |
| Solubility In Organic Solvents | Soluble in common organic solvents like dichloromethane, chloroform |
| Odor | Likely has a characteristic organic - chemical odor |
| Stability | Stable under normal conditions, but may react with strong oxidizing or reducing agents |
As an accredited (S)-2,4-Dichloro-A-(Chloromethyl)-Benzenemethanol factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.
| Packing | 500g of (s)-2,4 - dichloro - a-(chloromethyl) - benzenemethanol in sealed chemical - grade container. |
| Storage | (s)-2,4 - Dichloro-α-(chloromethyl) - benzenemethanol should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. It should be kept in a tightly sealed container to prevent moisture and air exposure, which could potentially lead to decomposition. Store it separately from incompatible substances such as oxidizing agents and bases to avoid chemical reactions. |
| Shipping | (±)-2,4 - Dichloro - α-(chloromethyl) - benzenemethanol should be shipped in accordance with strict chemical transport regulations. It must be in a well - sealed, appropriate container to prevent leakage, with clear hazard labels, and transported by carriers licensed for such chemicals. |
Competitive (S)-2,4-Dichloro-A-(Chloromethyl)-Benzenemethanol prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615365006308 or mail to info@alchemist-chem.com.
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Tel: +8615365006308
Email: info@alchemist-chem.com
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What is the chemical structure of (s) -2,4 -dichloro - a- (chloromethyl) -benzenemethanol?
The chemical structure of (s) -2,4-dichloro - α - （ chloromethyl) -benzyl alcohol is a research subject in the field of organic chemistry. The structure of this compound can be derived from its name.
"2,4-dichloro", it is stated that above the benzene ring, one chlorine atom is connected to each of the second and fourth positions. The chlorine atom is electronegative, which affects the electron cloud distribution of the benzene ring and alters the chemical activity and reaction characteristics of the benzene ring.
“α - （ chloromethyl) ", shown in the α position of the benzene ring, that is, on the carbon atom directly connected to the benzene ring, there is a monochloromethyl (-CH -2 Cl) group. This chloromethyl group, in which the chlorine atom gives the group a certain polarity and reactivity, can participate in many chemical reactions, such as nucleophilic substitution reactions.
"Benzyl alcohol" indicates that the basic skeleton of the compound is benzene ring-linked hydroxy methyl (-CH 2O OH). Hydroxy (-OH) is hydrophilic, which makes the compound have a certain polarity and can form hydrogen bonds with water, which affects its physical properties, such as solubility.
In general, the chemical structure of (s) -2,4-dichloro - α - （ chloromethyl) -benzyl alcohol is composed of benzene ring as the core, and there are chlorine atoms at specific positions, chloromethyl and hydroxymethyl groups. The interaction of each group endows the compound with unique chemical and physical properties, and may have important significance and application value in organic synthesis, medicinal chemistry and other fields.
"2,4-dichloro", it is stated that above the benzene ring, one chlorine atom is connected to each of the second and fourth positions. The chlorine atom is electronegative, which affects the electron cloud distribution of the benzene ring and alters the chemical activity and reaction characteristics of the benzene ring.
“α - （ chloromethyl) ", shown in the α position of the benzene ring, that is, on the carbon atom directly connected to the benzene ring, there is a monochloromethyl (-CH -2 Cl) group. This chloromethyl group, in which the chlorine atom gives the group a certain polarity and reactivity, can participate in many chemical reactions, such as nucleophilic substitution reactions.
"Benzyl alcohol" indicates that the basic skeleton of the compound is benzene ring-linked hydroxy methyl (-CH 2O OH). Hydroxy (-OH) is hydrophilic, which makes the compound have a certain polarity and can form hydrogen bonds with water, which affects its physical properties, such as solubility.
In general, the chemical structure of (s) -2,4-dichloro - α - （ chloromethyl) -benzyl alcohol is composed of benzene ring as the core, and there are chlorine atoms at specific positions, chloromethyl and hydroxymethyl groups. The interaction of each group endows the compound with unique chemical and physical properties, and may have important significance and application value in organic synthesis, medicinal chemistry and other fields.
What are the physical properties of (s) -2,4 -dichloro - a- (chloromethyl) -benzenemethanol?
The physical properties of (s) -2,4-dichloro - α - （ chloromethyl) -benzyl alcohol are of great value for investigation.
Looking at its morphology, at room temperature, it is mostly white to off-white crystalline powder with fine texture and is quite pure. This state makes it easy to handle and measure in many operations and applications.
When talking about the melting point, it is about [specific melting point value] degrees Celsius. This melting point characteristic is a key indicator in the identification and purity judgment of the substance. When heated, it melts at a specific temperature, so that its purity can be determined.
Solubility is also an important physical property. In organic solvents such as ethanol and acetone, it exhibits good solubility and can quickly fuse with solvents to form a uniform system. However, in water, the solubility is relatively limited and only a little can be dissolved. This difference in solubility has far-reaching implications in separation, purification and preparation.
Its density has been determined to be about [specific density value] g/cm3. This parameter is related to the distribution and behavior of substances in the mixed system, and is of great significance to chemical production and material applications.
In addition, the stability of (s) -2,4-dichloro - α - （ chloromethyl) -benzyl alcohol is also worthy of attention. Under normal environmental conditions, it has a certain degree of chemical stability. However, under extreme conditions such as strong acids, alkalis, or high temperatures, its structure and properties may change. This requires attention during storage and use.
Looking at its morphology, at room temperature, it is mostly white to off-white crystalline powder with fine texture and is quite pure. This state makes it easy to handle and measure in many operations and applications.
When talking about the melting point, it is about [specific melting point value] degrees Celsius. This melting point characteristic is a key indicator in the identification and purity judgment of the substance. When heated, it melts at a specific temperature, so that its purity can be determined.
Solubility is also an important physical property. In organic solvents such as ethanol and acetone, it exhibits good solubility and can quickly fuse with solvents to form a uniform system. However, in water, the solubility is relatively limited and only a little can be dissolved. This difference in solubility has far-reaching implications in separation, purification and preparation.
Its density has been determined to be about [specific density value] g/cm3. This parameter is related to the distribution and behavior of substances in the mixed system, and is of great significance to chemical production and material applications.
In addition, the stability of (s) -2,4-dichloro - α - （ chloromethyl) -benzyl alcohol is also worthy of attention. Under normal environmental conditions, it has a certain degree of chemical stability. However, under extreme conditions such as strong acids, alkalis, or high temperatures, its structure and properties may change. This requires attention during storage and use.
What are the main uses of (s) -2,4 -dichloro - a- (chloromethyl) -benzenemethanol?
(S) - 2,4 -dichloro - α - （ chloromethyl) -benzyl alcohol, this substance has a wide range of uses. In the field of pharmaceutical synthesis, it is often used as a key intermediate. Due to its special chemical structure, it can derive compounds with specific pharmacological activities through various chemical reactions, and then lay the foundation for the creation of new drugs.
In the field of materials science, it also has its uses. Or it can be processed by a specific process and incorporated into polymer materials to optimize the properties of materials in terms of stability and corrosion resistance. For example, in the preparation of some special coating materials, after adding this substance, the coating's resistance to environmental erosion is enhanced and the service life of the material is extended.
Furthermore, in the field of organic synthetic chemistry, as an important organic reagent, it can participate in the construction of many complex organic compounds. Chemists can use its active functional groups to ingeniously design reaction pathways and synthesize organic molecules with complex structures and unique functions, which help organic chemistry research continuously expand the boundaries and provide powerful tools for exploring new substances and properties.
In the field of materials science, it also has its uses. Or it can be processed by a specific process and incorporated into polymer materials to optimize the properties of materials in terms of stability and corrosion resistance. For example, in the preparation of some special coating materials, after adding this substance, the coating's resistance to environmental erosion is enhanced and the service life of the material is extended.
Furthermore, in the field of organic synthetic chemistry, as an important organic reagent, it can participate in the construction of many complex organic compounds. Chemists can use its active functional groups to ingeniously design reaction pathways and synthesize organic molecules with complex structures and unique functions, which help organic chemistry research continuously expand the boundaries and provide powerful tools for exploring new substances and properties.
What are the synthesis methods of (s) -2,4 -dichloro - a- (chloromethyl) -benzenemethanol?
The synthesis method of (s) -2,4-dichloro-a- (chloromethyl) -benzyl alcohol has many paths to follow in the field of organic synthesis today.
One of them can be started from the corresponding halogenated benzaldehyde. First, a specific halogenating agent is used to introduce chlorine atoms into the benzaldehyde ring at a specific position under suitable reaction conditions to obtain 2,4-dichlorobenzaldehyde. This halogenation reaction requires precise temperature control, control of the reaction time, and selection of suitable solvents and catalysts to improve the reaction yield and selectivity. Then, 2,4-dichlorobenzaldehyde is reacted with chloromethylation reagents, such as chloromethyl methyl ether, in an alkali-catalyzed environment, so that the α-position of the aldehyde group is introduced into the chloromethyl group, and then through the reduction step, with a suitable reducing agent, such as sodium borohydride, etc., the aldehyde group is reduced to the methanol group, and the final target product (s) -2,4-dichloro-a- (chloromethyl) -benzyl alcohol is obtained. This path step is clear, but the control of the reaction conditions of each step is crucial.
Second, benzyl alcohol derivatives can also be used as the starting material. First, the benzyl ring of benzyl alcohol is halogenated to achieve 2,4-position dichloro substitution. Chloromethyl was introduced into the side chain of the benzene ring by chloromethylation. In this synthesis strategy, the choice of raw materials is relatively flexible, but the choice of halogenation and chloromethylation sequence needs to be carefully considered according to the characteristics of the raw materials and reaction expectations.
In addition, there is a strategy that uses Grignard reagents. Grignard reagents are prepared by reacting halogenated benzene with magnesium, and react with carbonyl compounds containing chloromethyl to form carbon-carbon bonds. Subsequent steps such as hydrolysis and reduction yield (s) - 2,4 - dichloro - a - (chloromethyl) - benzyl alcohol. Although this method can effectively construct complex structures, the preparation and reaction conditions of Grignard's reagent are strict, and the requirements for anhydrous and anaerobic environments are quite high.
All synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively weigh the availability of raw materials, cost, reaction conditions and product purity, and choose the optimal method to achieve the purpose of efficient synthesis of (s) -2,4-dichloro-a- (chloromethyl) -benzyl alcohol.
One of them can be started from the corresponding halogenated benzaldehyde. First, a specific halogenating agent is used to introduce chlorine atoms into the benzaldehyde ring at a specific position under suitable reaction conditions to obtain 2,4-dichlorobenzaldehyde. This halogenation reaction requires precise temperature control, control of the reaction time, and selection of suitable solvents and catalysts to improve the reaction yield and selectivity. Then, 2,4-dichlorobenzaldehyde is reacted with chloromethylation reagents, such as chloromethyl methyl ether, in an alkali-catalyzed environment, so that the α-position of the aldehyde group is introduced into the chloromethyl group, and then through the reduction step, with a suitable reducing agent, such as sodium borohydride, etc., the aldehyde group is reduced to the methanol group, and the final target product (s) -2,4-dichloro-a- (chloromethyl) -benzyl alcohol is obtained. This path step is clear, but the control of the reaction conditions of each step is crucial.
Second, benzyl alcohol derivatives can also be used as the starting material. First, the benzyl ring of benzyl alcohol is halogenated to achieve 2,4-position dichloro substitution. Chloromethyl was introduced into the side chain of the benzene ring by chloromethylation. In this synthesis strategy, the choice of raw materials is relatively flexible, but the choice of halogenation and chloromethylation sequence needs to be carefully considered according to the characteristics of the raw materials and reaction expectations.
In addition, there is a strategy that uses Grignard reagents. Grignard reagents are prepared by reacting halogenated benzene with magnesium, and react with carbonyl compounds containing chloromethyl to form carbon-carbon bonds. Subsequent steps such as hydrolysis and reduction yield (s) - 2,4 - dichloro - a - (chloromethyl) - benzyl alcohol. Although this method can effectively construct complex structures, the preparation and reaction conditions of Grignard's reagent are strict, and the requirements for anhydrous and anaerobic environments are quite high.
All synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively weigh the availability of raw materials, cost, reaction conditions and product purity, and choose the optimal method to achieve the purpose of efficient synthesis of (s) -2,4-dichloro-a- (chloromethyl) -benzyl alcohol.
What are the precautions for (s) -2,4 -dichloro-a- (chloromethyl) -benzenemethanol during storage and transportation?
(S) -2,4 -dichloro - α - （ chloromethyl) -benzyl alcohol in storage and transportation, need to pay attention to many key matters. This is an organic compound, the nature is quite active.
When storing, choose the first environment. It should be placed in a cool and ventilated place, away from fire and heat sources. Because it is quite sensitive to heat, it is easy to decompose or cause other chemical reactions when heated, which endangers safety. And it needs to be stored separately from oxidants, acids, alkalis, etc., to avoid mixed storage to prevent violent reactions. Warehouse humidity should be controlled in an appropriate range, too high or too low humidity may affect its stability.
Furthermore, the packaging must be tight. Use packaging materials that meet standards to prevent leakage. If the packaging is damaged, not only will the substance be lost, but it may also pollute the environment and pose a threat to the health of surrounding personnel.
During transportation, caution should also be taken. Transportation vehicles should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. When driving, it is necessary to ensure smooth operation and avoid severe bumps and vibrations to prevent damage to the packaging. Transport personnel also need professional training to be familiar with the characteristics of the substance and emergency treatment methods. The loading and unloading process must be light and light. It is strictly forbidden to drop, heavy pressure and friction to prevent the packaging from cracking due to external forces and causing leakage accidents.
In short, (S) -2,4 -dichloro - α - （ chloromethyl) -benzyl alcohol must follow strict specifications and operating procedures throughout the storage and transportation process to ensure the safety of personnel, environmental safety and the stability of the substance itself.
When storing, choose the first environment. It should be placed in a cool and ventilated place, away from fire and heat sources. Because it is quite sensitive to heat, it is easy to decompose or cause other chemical reactions when heated, which endangers safety. And it needs to be stored separately from oxidants, acids, alkalis, etc., to avoid mixed storage to prevent violent reactions. Warehouse humidity should be controlled in an appropriate range, too high or too low humidity may affect its stability.
Furthermore, the packaging must be tight. Use packaging materials that meet standards to prevent leakage. If the packaging is damaged, not only will the substance be lost, but it may also pollute the environment and pose a threat to the health of surrounding personnel.
During transportation, caution should also be taken. Transportation vehicles should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. When driving, it is necessary to ensure smooth operation and avoid severe bumps and vibrations to prevent damage to the packaging. Transport personnel also need professional training to be familiar with the characteristics of the substance and emergency treatment methods. The loading and unloading process must be light and light. It is strictly forbidden to drop, heavy pressure and friction to prevent the packaging from cracking due to external forces and causing leakage accidents.
In short, (S) -2,4 -dichloro - α - （ chloromethyl) -benzyl alcohol must follow strict specifications and operating procedures throughout the storage and transportation process to ensure the safety of personnel, environmental safety and the stability of the substance itself.
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